As fashionable as your skinny jeans might be, it’s better to mix them up and wear looser pants and take them off as soon as you get home. Spending too much time wearing tight jeans, especially if you’re moving or squatting throughout the day, can hurt the muscles and nerves in your legs. The combination of skinny jeans and tight belts can also cause numbness, pain, and tingling on the front of your thighs, a condition also known as Skinny Pant Syndrome.