He made his debut for the club on 2 February 2016 playing in a 3–0 friendly win against Chinese side Jiangsu Sainty. Ezatolahi scored his first goal for Rostov on 27 February 2016 in a 2–0 friendly win against Norwegian side Stabæk.On 26 July 2016, Ezatolahi made his first start for Rostov in an official game in the first leg of the 2016–17 UEFA Champions League third qualifying round against R.S.C. Anderlecht and scored a goal in the 16th minute, equalizing the score to 1–1. In the second half of the game, another shot by him from outside of the box was denied by the crossbar, and the game ended with a score of 2–2. He is the first scorer of the club in a European match (not counting the UEFA Intertoto Cup) and also the youngest ever Iranian player to score at the Champions League.